Knochenaufbau während der Stillzeit: Wie ein Gehirnhormon das Skelett regeneriert

Das mütterliche Skelett hat die faszinierende Fähigkeit, sich während der Stillzeit rasch zu erholen. Das Gehirnhormon CCN3 wird während des Stillens aus dem Hypothalamus freigesetzt und wirkt wie ein Turbo für die Knochenregeneration. Aus dieser Erkenntnis ergeben sich vielfältige, potenzielle Einsatzmöglichkeiten. Diese hat Prof. Lorenz Hofbauer nun in einem Artikel im New England Journal of Medicine erläutert und eingeordnet.

### Background Research for the Article

The press release highlights a significant finding in the field of maternal health and bone regeneration, particularly during the postpartum period when women are breastfeeding. The central focus is on CCN3, a brain hormone released from the hypothalamus that appears to play a crucial role in promoting bone healing and recovery in mothers who are nursing.

– **Bone Health During Pregnancy and Lactation**: During pregnancy, a woman’s body undergoes numerous changes to support both her health and that of her developing fetus. This includes increased calcium demands for fetal bone development. After childbirth, particularly during lactation (breastfeeding), mothers may experience changes in bone density due to calcium being transferred to breast milk.

– **Impact of Lactation on Bone Density**: Studies have indicated that women can lose up to 15% of their total body calcium stores while breastfeeding due to an increase in dietary needs and hormonal shifts. However, many women’s bones demonstrate remarkable resilience, with some studies showcasing recovery after lactation ends.

– **Role of Hormones**: Hormones such as estrogen drop significantly postpartum but return gradually as hormone levels stabilize with weaning. CCN3 is now highlighted as an important factor influencing this dynamic by aiding bone regeneration at critical times during lactation.

– **Potential Applications**: The findings suggest potential therapeutic avenues if CCN3 can be isolated or harnessed for medical treatments aimed at improving or accelerating bone healing processes not only for postpartum mothers but also potentially for other populations suffering from osteoporosis or fractures.

### FAQ for the Article

1. **What is CCN3?**
– CCN3 (Cellular Communication Network Factor 3) is a brain-derived hormone released by the hypothalamus, chiefly noted for its role in enhancing bone regeneration during nursing.

2. **How does breastfeeding affect maternal bones?**
– Breastfeeding increases nutrient demands like calcium; consequently, many mothers experience temporary reductions in their bone mineral density but have shown remarkable capacity to recover over time.

3. **What evidence supports this study?**
– The assertion comes from recent research conducted by Prof. Lorenz Hofbauer published in *New England Journal of Medicine*, which elaborates on how CCN3 assists bones while nursing occurs.

4. **Can this discovery lead to treatments beyond postpartum care?**
– Yes! There are hopeful implications where utilizing insights around CCN3 could benefit those with circumstances related to low bone density like osteoporosis or recovery from fractures across various age groups and situations beyond just new mothers.

5. **Is it safe if I am breastfeeding? Will it impact my baby?**
– While understanding still needs further exploration about direct supplementation related safety measures regarding any hormones including CCN3 must be consulted with healthcare providers before considering any medical interventions.

6. **What should new moms do about their diet post-delivery regarding milk production vs maintaining their health?**
– New moms should focus on balanced diets rich in vital nutrients including calcium alongside guidance from healthcare professionals specific nutrition advice appropriate throughout breastfeeding phases.

7.**How might researchers study further into utilising benefits associated with hormones like CCN3 more broadly?
* Investigative advances will likely involve longitudinal studies focusing on potential clinical trials targeting populations affected by various forms of compromised skeletal integrity aiming toward evaluating efficacy alongside safety profiles iteratively over extended periods working towards conclusive results pertaining simply called exploratory pathways.*

8.*Are there lifestyle recommendations based upon these findings?
*Elements include ensuring physical activity commensurate within capabilities introduced gradually alongside participation encouragement through tailored exercise programs might pivot towards addressing supportive wellness alternatives further reinforcing healthy lifestyles overall keeping vigilant attention onto mental well-being’s attachment seamlessly throughout diverse facets coexisting harmoniously*

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Originamitteilung:

Das mütterliche Skelett hat die faszinierende Fähigkeit, sich während der Stillzeit rasch zu erholen. Das Gehirnhormon CCN3 wird während des Stillens aus dem Hypothalamus freigesetzt und wirkt wie ein Turbo für die Knochenregeneration. Aus dieser Erkenntnis ergeben sich vielfältige, potenzielle Einsatzmöglichkeiten. Diese hat Prof. Lorenz Hofbauer nun in einem Artikel im New England Journal of Medicine erläutert und eingeordnet.

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