Screening per Darmspiegelung: Unterschätzte Effekte durch verzögerte Krebsregistrierung

Zahlreiche Untersuchungen haben den Nutzen der Darmspiegelung (Koloskopie) als Darmkrebsvorsorge dokumentiert. Auch die bislang einzige kontrollierte Langzeit-Studie zu dieser Frage belegt die Wirksamkeit, allerdings waren die berichteten Effekte geringer als erwartet. Epidemiologen vom Deutschen Krebsforschungszentrum (DKFZ) zeigen, dass die Effekte der Koloskopie in dieser Studie wahrscheinlich erheblich unterschätzt wurden. Ein wesentlicher Grund ist die verzögerte Erfassung der Krebsfälle in den Krebsregistern.

## Background Research for the Article

**Colonoscopy and Colorectal Cancer Screening**
Colorectal cancer is one of the leading causes of cancer-related mortality globally. Early detection through screening can significantly reduce mortality rates by identifying pre-cancerous polyps and early-stage cancers when they are most treatable. Colonoscopy, a procedure that allows doctors to examine the interior of the colon, has emerged as a crucial tool in screening for colorectal cancer.

Various studies have demonstrated the effectiveness of colonoscopy in reducing colorectal cancer incidence and mortality. The procedure involves inserting a long, flexible tube with a camera into the rectum to visualize potential abnormalities. When polyps or suspicious lesions are found during this examination, they can often be removed before they develop into cancer.

Despite substantial evidence supporting its effectiveness, findings from some studies indicated that overall reductions in cancer rates were lower than anticipated following widespread implementation of colonoscopy screenings.

**Delayed Cancer Registration**
The article discusses an important yet often-overlooked aspect: delayed registration of newly diagnosed cancers within national databases or registries. These delays can skew results regarding the efficacy of screening programs like colonoscopy because there may be an essential lag time between patient diagnosis and when that information is officially recorded.

Epidemiologists from Germany’s National Center for Cancer Research (DKFZ) have examined these registration timelines more closely and suggest that many benefits associated with regular colonoscopies may not be fully captured due to these delays. By failing to account for this lag, previous studies might correctly report lower-than-expected outcomes regarding diving down numbers related to colorectal incidents and mortalities directly attributable to routine screenings.

## FAQ Section

### Frequently Asked Questions (FAQ)

#### 1. What is a colonoscopy?
A colonoscopy is a medical procedure used to examine the inner lining of your large intestine (colon) and rectum using a long, flexible tube called a colonoscope equipped with cameras.

#### 2. Why is screening via colonoscopy important?
Screening through colonscopies helps detect pre-cancerous polyps or early-stage colorectal cancers at an earlier stage when treatment can be most effective—increasing survival rates significantly among those screened compared to those who are not screened!

#### 3. What benefits does it offer?
The primary benefits include identifying abnormal growths before they become malignant, diagnosing existing cancers at earlier stages – which generally leads towards improved treatment options & better prognosis!

#### 4. What did recent research by DKFZ find about previous studies on colonscopy effectiveness?
The German Cancer Research Center concluded that prior assessments reporting lesser impacts on preventing death from colorectal cancer potentially underestimated true effects largely due repetitive delays in registering incidents within predominant data sources like national health registries.

#### 5. How do delays in cancer detection impact study results?
When new cases aren’t recorded promptly in health organization statistics—crucial data regarding successful prevention efforts gets misplaced; thus creating ill-reflected conclusions about how effective initiatives such as regular screenings really might be over time despite ongoing proven success via clinical practices shown elsewhere!

#### 6 .What should I do if I’m due for my next screening test?
Consult your healthcare professional immediately! Regular check-ups based on age (generally starting around age fifty unless there’s family history suggesting earlier intervention needed!) will help determine timing/schedule & ensure personal safety monitoring through lifesaving tests frequent enough based upon established guidelines provided initially during consultations done periodically thereafter too.

Originamitteilung:

Zahlreiche Untersuchungen haben den Nutzen der Darmspiegelung (Koloskopie) als Darmkrebsvorsorge dokumentiert. Auch die bislang einzige kontrollierte Langzeit-Studie zu dieser Frage belegt die Wirksamkeit, allerdings waren die berichteten Effekte geringer als erwartet. Epidemiologen vom Deutschen Krebsforschungszentrum (DKFZ) zeigen, dass die Effekte der Koloskopie in dieser Studie wahrscheinlich erheblich unterschätzt wurden. Ein wesentlicher Grund ist die verzögerte Erfassung der Krebsfälle in den Krebsregistern.

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